Non-invasive d-dimer rapid test kit using method

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  • D-dimer - Siemens Healthineers

    2021-7-6 · The D-dimer assay on the Stratus ® CS Analyzer is an in vitro diagnostic test for the quantitative measurement of cross-linked fibrin degradation products (D-dimer) in human citrated or heparinized plasma. The Stratus CS D-dimer assay is intended for use in conjunction with a non-high clinical pretest probability (PTP) assessment model to exclude pulmonary embolism (PE) disease and …

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  • A comparison of three rapid D-dimer methods for the ...

    We compared three rapid D-dimer methods for the diagnosis of venous thromboembolism. Patients presenting to four teaching hospitals with the possible diagnosis of deep vein thrombosis or pulmonary embolism were investigated with a combination of clinical likelihood, D-dimer (SimpliRED) and initial non-invasive …

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  • A comparison of three rapid D‐dimer methods for the ...

    2008-8-9 · IL‐Test d ‐dimer is an automated method for measuring D‐dimer quantitatively. All automated testing was performed on the AMAX CS 190 (Sigma Diagnostics). The kit contains a latex reagent, reaction buffer and a calibrator.

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  • Performance of a new, fast D-dimer test (IL Test™ D

    1999-5-1 · The method can be evaluatedin prospective clinical trials to test its usefulness, in combinationwith other non-invasive diagnostic procedures, in the managementof DVT diagnosis. INTRODUCTION Non-invasivemethods,such as impedenceplethysmo- graphyandcompressionultrasonography,are now widely used to diagnose proximal deep vein thrombosis …

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  • Contribution of a new, rapid, quantitative and

    Ninety-nine consecutive outpatients with symptoms suggestive of deep vein thrombosis (DVT) were tested for the presence of D-dimer using a new, rapid method (BC D-Dimer) based on the agglutination principle and performed on a BCT analyzer. Dimertest Gold EIA and VIDAS D-Dimer devices were used as comparative methods.

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  • d-Dimer Testing in Laboratory Practice | Clinical ...

    D-dimer adalah produk degradasi fibrin cross-linked yang terbentuk selama aktivasi sistem koagulasi. Ini biasanya digunakan untuk mendiagnosis penyakit tromboemboli pada pasien rawat jalan yang dicurigai memiliki deep venous thrombosis (DVT) dan emboli paru (PE). Kit ini merupakan kit alternative yang cepat dan bersifat non-invasive , D-dimer telah terbukti membantu dalam mendeteksi Vena ...

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  • D-Dimer

    2019-3-27 · The Alere Triage® D-Dimer Test has been standardized using a purified protein preparation of D-dimer based on the mass (concentration) of the analyte present in EDTA anticoagulated plasma. The D-dimer values are presented in units of mass (ng/mL) of D-dimer, also known as D-dimer Units (D …

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  • Alere Triage D-Dimer Test Product Insert (PI), English

    2020-7-27 · In the meta-analysis of 13 cohort studies (including the current study), patients with severe disease had an increase in mean D-dimer value by 0.91 (95% confidence interval, 0.51–1.31, p < 0.001) μg/ml compared to those with non-severe disease, and odds of severe infection was associated with D-dimer greater than 0.5 μg/ml (odds ratio = 5.78, 95% confidence interval, 2.16–15.44, p < 0.001) on …

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  • Quidel Triage D-Dimer Test | Quidel

    2011-9-1 · d-dimer is a specific product of the degradation of fibrin clots that results from the action of 3 enzymes: (a) thrombin, generated from the activation of the coagulation cascade that converts fibrinogen into fibrin clots; (b) activated factor XIII that cross-links fibrin clots by means of covalent bonds between fibrin monomers; and (c) plasmin, the ultimate enzyme of fibrinolysis that ...

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  • d-Dimer Testing in Laboratory Practice | Clinical ...

    2002-11-1 · A new method for measuring D-dimer using immunoturbidity: a study of 255 patients with suspected PE and DVT. Blood Coag Fibrinolys. 2000;11:715-721. 7. Shitrit D, Heyd J, Raveh D, Rudensky B. Diagnostic value of the D-dimer test in deep vein thrombosis: improved results by a new assay and by using discriminate levels. Thromb Res. 2001;102:125-131.

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  • D-dimer: Establishing a laboratory assay for ruling out ...

    D-dimers are formed by the breakdown of fibrinogen and fibrin during fibrinolysis. D-dimer analysis is critical for the diagnosis of deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. Modern assays for D-dimer are monoclonal antibody based. The enzyme-linked immunosorbent assay (ELISA) is the reference method ...

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  • Widely Used Types and Clinical Applications of D

    2003-12-5 · By Susan L. Taylor, MS, MT (ASCP), MBA. In September 2003, the VIDAS® D-Dimer New™ from bioMerieux was approved by the United States Food and Drug Administration (FDA) for use in excluding a diagnosis of deep-vein thrombosis (DVT) when used in conjunction with a pre-test probability model (Figure 1) and to aid in the diagnosis of pulmonary embolism (PE) in outpatients.

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  • Safely Excluding DVT With VIDAS - Clinical Lab Products

    2021-6-10 · ABBOTT - The RHEUMATEX™ test provides a simple rapid screening or quantitative method of detection of rheumatoid factor in serum . Latex ... PF1051KUSA PF1051-KUS D-Dimer test kit 60/bx PF1071KUSA PF1071-KUS hsCRP test kit 60/bx PF1111-KA PF1111-K Myo-II test kit 60/bx PF1061KUSA PF1061-KUS NTproBNP test kit 60/bx

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  • Laboratory products for your Rapid Diagnostics and

    2020-7-27 · Differences of mean value of D-dimer between severe and non-severe group was 0.91 μg/ml (95% confidence interval CI, 0.51–1.31, p < 0.001, I 2 = 94.7%), after pooling WMD for these studies, as shown in Fig. 3, suggesting a significant increase of D-dimer level in patients with severe disease than those with non-severe disease, on admission.

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  • D-dimer level is associated with the severity of COVID

    2014-1-1 · The aim of this study was to establish a non-invasive, rapid method to genotype apolipoprotein E gene polymorphisms. Genomic DNA from mouth swab specimens was extracted using magnetic nanoparticles, and genotyping was performed by real-time PCR using TaqMan-BHQ probes. Genotyping accuracy was validated by DNA sequencing.

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  • A non-invasive, rapid method to genotype late-onset ...

    SARS-CoV-2 Antigen Rapid Test Kit (Colloidal Gold) Package and Specification. 25 tests/kit (1 test/bag x 25 bags) Description. In vitro qualitative detection of SARS-CoV-2 nucleocapsid antigen in swab specimen within the first 5-7 days after onset of COVID-19 symptoms. Product Advantages. 1. Nasopharynx swab specimen, non-invasive. 2. Very ...

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  • D-dimer: Establishing a laboratory assay for ruling out ...

    2002-11-1 · A new method for measuring D-dimer using immunoturbidity: a study of 255 patients with suspected PE and DVT. Blood Coag Fibrinolys. 2000;11:715-721. 7. Shitrit D, Heyd J, Raveh D, Rudensky B. Diagnostic value of the D-dimer test in deep vein thrombosis: improved results by a new assay and by using discriminate levels. Thromb Res. 2001;102:125-131.

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  • D-dimer - Blood Test Results Explained - Lab Tests

    2021-3-31 · D-dimer tests are ordered, along with other laboratory tests and imaging scans, to help rule out, diagnose, and monitor diseases and conditions that cause hypercoagulability, a tendency to clot inappropriately.One of the most common of these conditions is DVT (deep vein thrombosis), which involves clot formation in the deep veins of the body, most frequently in the legs.

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  • A non-invasive, rapid method to genotype late-onset ...

    2014-1-1 · The aim of this study was to establish a non-invasive, rapid method to genotype apolipoprotein E gene polymorphisms. Genomic DNA from mouth swab specimens was extracted using magnetic nanoparticles, and genotyping was performed by real-time PCR using TaqMan-BHQ probes. Genotyping accuracy was validated by DNA sequencing.

    Get Price
  • DiaCarta Obtains Exclusive License for Non-Invasive

    2015-4-17 · DiaCarta Inc., a precision molecular diagnostics company and leading developer of novel oncology tests using liquid biopsy today announced the publication of a study entitled “A Rapid SARS-CoV-2 Variant Detection by Molecular-Clamping Based RT-qPCR” in MedRxiV that demonstrates the enhanced sensitivity and specificity using its proprietary XNA based Molecular Clamping Technology …

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  • The 5 Best At-Home Celiac Testing Kits | Testing.com

    2021-3-5 · The kit’s cutting edge technology uses next-generation sequencing in partnership with CAP/CLIA-certified PacificDx labs in Irvine, California. This DNA test kit uses cheek swabs to collect test material. The result is a non-invasive, pain-free method that takes just a few seconds to complete.

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  • (PDF) D-dimer in the diagnostic workup of suspected ...

    D-dimer levels are elevated not only in the setting of acute thrombosis, but also in other conditions such as preg- REFERENCES nancy, infection and malignancy. In contrast, a negative result using a sensitive D-dimer test is useful for excluding acute 1. Heit JA, Minor …

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  • Non-invasive cell classification using the Paint Raman ...

    2021-4-23 · Using the mapping method, characteristic signals can be obtained in subcellular region or intracellular organelles, and it is also possible to obtain features suitable for cell classification ...

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  • Different types of COVID-19 tests explained

    2020-11-12 · UC Davis Health has helped lead the way in COVID-19 testing and now is among the first in the U.S. with a rapid combined COVID/flu test. The rapid point-of-care test is a PCR-based method, which is similar to what UC Davis Health has used in its lab since March, running hundreds of tests a day, often delivering results in hours.

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  • Clinical decision support tool and rapid point-of-care ...

    2020-6-3 · D-Dimer, mg L −1: 2.4 (0.6–14.4) 0.5 (0.3–0.8) PCT, ng mL −1: 0.1 (0.1–0.4) 0.1 (0.1–0.1) Wang et al. 5: ICU (n = 36) vs. non-ICU (n = 102) cTnI, pg mL −1: 11.0 (5.6–26.4) 5.1 (2.1–9.8) D-Dimer, mg L −1: 414 (191–1324) 166 (101–285) CK–MB, U L −1: 18 (12–35) 13 (10–14) PCT ≥ 0.05 ng mL −1: 27 (75.0) 22 (21.6 ...

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  • D-dimer Assay Issues and Standardization: QMP-LS Studies

    2017-10-1 · How D-dimer Tests Evolved • Early test systems used polyclonal antibodies generated to a variety of fibrin and fibrinogen split products • Today, methods rely on use of Mabs which recognize epitopes specific to cross-linked D-dimer fragment • Assays are readily available, economical, non-invasive, rapid and easy to perform 13

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  • Relationship between disease severity and D-dimer

    2010-6-30 · Pulmonary embolism (PE) is diagnosed with increasing frequency nowadays due to advances in the diagnostic methods and the increased awareness of the disease. There is a tendency to use non invasive diagnostic methods for all diseases. D-dimer is a fibrin degradation product. We aimed to detect the relationship between disease severity and the D-dimer levels measured with two different …

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  • Verification of automated latex-enhanced particle ...

    Introduction. D-dimer is a final plasmin-mediated fibrin degradation product consisting of two covalently bound fibrin D domains, cross-linked by factor XIII during clot formation (1-3).In conjunction with clinical pre-test probability, measurement of D-dimers is a key non-invasive diagnostic test to rule out venous thromboembolism (VTE) and pulmonary embolism (PE), as well as an aid in the ...

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  • Combination of a Normal D-Dimer Concentration and

    In this test, the CV of D-dimer determination is between 1.4% and 2%, in good correlation with those reported by others using the same technique as that used here for SF evaluation (Lia-test): indeed, the D-dimer coefficient of variation (CV) depends on D-dimer concentration; and at mean levels of 170 ng/mL and 2,400 ng/mL the reported CV were ...

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  • New Combinational Assay Using Soluble Fibrin and D

    2020-7-21 · We further performed a covariate analysis using the Kruskal-Wallis test (with post-hoc testing) on patient age, patient sex, collection date, collection site, smoking status, non-cancer disease ...

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  • Evaluation of the Simplify d-dimer assay as a

    2021-4-23 · Using the mapping method, characteristic signals can be obtained in subcellular region or intracellular organelles, and it is also possible to obtain features suitable for cell classification ...

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  • Non-invasive early detection of cancer four years

    2020-9-24 · As shown in Table 2, using the cutoff value of 200 ng/mL irrespective of the patient’s age, the proportion of patients with a negative d-dimer test was 57.6% and 60.9%, and the NNT to find 1 normal d-dimer test was 1.7 and 1.6 with the CA-7000 and CS-2100, respectively. No …

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  • Non-invasive cell classification using the Paint Raman ...

    Wastewater Surveillance Program. Wastewater-Based Epidemiology (WBE) is a technique that can be used to help in the fight against COVID-19, allowing for rapid, non-invasive insights into the health of large or targeted populations including municipalities, senior care homes and dormitories.

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  • Quidel Triage D-Dimer Test | Quidel

    Introduction. D-dimer is a final plasmin-mediated fibrin degradation product consisting of two covalently bound fibrin D domains, cross-linked by factor XIII during clot formation (1-3).In conjunction with clinical pre-test probability, measurement of D-dimers is a key non-invasive diagnostic test to rule out venous thromboembolism (VTE) and pulmonary embolism (PE), as well as an aid in the ...

    Get Price
  • Verification of automated latex-enhanced particle ...

    2013-8-1 · Participants who offered only a qualitative D-dimer test indicated that the most common reason for this practice was lack of an automated instrument to perform a more sensitive quantitative D-dimer test. Of those laboratories reporting a qualitative method, 110 (27%) recommend using a qualitative D-dimer test to exclude VTE.

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  • D-dimer: Simple Test, Tough Problems | Archives of ...

    2016-4-13 · DiaCarta and Pangaea Biotech S.L have signed a long term agreement to launch in the U.S.A and China a non-invasive test to detect genetic material in blood of cancer patients, a technique known as ‘liquid biopsy’.

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  • DiaCarta and Pangaea Biotech Join Forces to

    2020-7-21 · We further performed a covariate analysis using the Kruskal-Wallis test (with post-hoc testing) on patient age, patient sex, collection date, collection site, smoking status, non-cancer disease ...

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  • Non-invasive early detection of cancer four years

    2009-8-14 · Cardiac D-dimer seems to be the only test with the capacity to exclude DVT in patients with a moderate pre-test probability (up to 27%; fig 4), although only four studies on Cardiac D-dimer were available and thus the 95% confidence interval exceeds 2%. The decision on which point of care D-dimer test to use depends on the setting.

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  • Excluding venous thromboembolism using point of

    2015-10-23 · INTRODUCTION. Non-invasive prenatal testing (NIPT), using methods of cell-free DNA (cfDNA) analysis, provides the most accurate assessment for fetal trisomies 21, 18 and 13, compared with screening methods that combine maternal age, and ultrasound and serum biochemical markers.

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  • Clinical evaluation of the IONA test: a non‐invasive ...

    16. A kit for diagnosing thromboembolic disease using a method according to claim 1, comprising: anti D-dimer monoclonal antibodies; a plasminogen activator with a high specificity for fibrin (Pa-Fb sp); a positive control sample for soluble fibrin and if appropriate a negative control sample. 17.

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  • DETECTION OF VENOUS THROMBOEMBOLIC

    2008-5-30 · D-dimer measurement. D-dimer was assayed using the quantitative, immuno-tubidimetric STA-Liatest D-dimer kit assay from Diagnostica Stago, Asnieres, France, which was run on an automatic coagulation analyzer (STA-compact, Diagnostica Stago) in …

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  • The value of ischemia-modified albumin compared

    Helicobacter pylori (H . pylori) as gram-negative and spiral microorganism is responsible for colonization in the gastric microniche for more than 50% of world population. Recent studies have shown a critical role of H. pylori in the development of peptic ulcers, gastric mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric cancer.

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